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Garcinia cambogia canada How Garcinia Cambogia Works Garcinia helps people lose weight through a variety of mechanisms. The principle active ingredient is called HCA, or hydroxycitric acid. This compound is a natural extract found in the leaves of the Malabar Tamarind plant. Pure Garcinia products also contain other natural GC extracts, such as Gorikapuli. However, the majority of the weight loss effects come from HCA.